Monday, August 17, 2015

Regular consumption of sugary drinks associated with type 2 diabetes


Sugar sweetened drinks may give rise to nearly 2 million diabetes cases over 10 years in the US and 80,000 in the UK
Regular consumption of sugar sweetened drinks is positively associated with type 2 diabetes independent of obesity status, finds a study published in The BMJ this week.
Artificially sweetened drinks and fruit juice also showed a positive association with type 2 diabetes, but the quality of evidence was limited. None the less, the authors warn that neither artificially sweetened drinks nor fruit juice are suitable alternatives to sugar sweetened drinks for the prevention of type 2 diabetes.
Artificially sweetened beverages have been seen as possible alternatives to sugar sweetened beverages to reduce intake of sugars and energy, and fruit juice has been considered a healthier alternative. However, evidence was not available to clarify whether or not consumption of each of sugar sweetened beverages, artificially sweetened beverages, and fruit juice is associated with risk of diabetes after taking account of obesity status.
To address this question, an international team of researchers led by the MRC Epidemiology Unit at Cambridge University set out to assess whether or not habitual consumption of sugar sweetened drinks, artificially sweetened drinks, or fruit juice was associated with the incidence of type 2 diabetes, and to estimate the 10-year risk attributable to sugar sweetened drinks in the USA and UK.
They analysed the results of 17 observational studies. Design and quality were taken into account to minimise bias. None of these was funded by industry.
They found that habitual consumption of sugar sweetened drinks was positively associated with incidence of type 2 diabetes, independently of obesity status.
The association between artificially sweetened drinks or fruit juice and incident type 2 diabetes was less evident. Yet, the researchers found little evidence for benefits of these beverages, and therefore concluded these drinks are unlikely to be healthy alternatives to sugar sweetened drinks for preventing type 2 diabetes.
They point out that the studies analysed were observational, so no definitive conclusions can be drawn about cause and effect.
However, assuming a causal association, they estimate that two million new-onset type 2 diabetes events in the USA and 80,000 in the UK from 2010 to 2020 would be related to consumption of sugar sweetened beverages.
“Although more research on cause and effect needs to be carried out, this study indicates the potential health gains that may be achieved by reducing the consumption of sugar sweetened drinks,” they conclude.
Link to article

Saturday, August 15, 2015

Miscellaneous Mnemonics


Miscellaneous Mnemonics


Resistor colour codes "Bad Boys Rape 
O
ur Young Girls But Violet Gives Willingly
Get Some Now":
· In ascending resistor value order:
Black: 0
Brown: 1
Red: 2
Orange: 3
Yellow: 4
Green: 5
Blue: 6
Violet: 7
Grey: 8
White: 9
Gold: 5%
Silver: 10%
None: 20%


Visible spectrum colors in order ROY G. BIV
· In order from low end of spectrum:
Red
Orange
Yellow
Green
Blue
Indigo
Violet
Alternatively: "Richard OYork Gained Battles
IVain" (Richard III was an English king defeated in 1485).


Ohm's Law "Virgins Are Rare":
Volts = Amps x Resistance
· Note: can then rearrange to more common form Resistance = Volts / Amps.


Ideal gas law "Pure Virgins Never Really
Tire":
PV=nRT


Electric units "Vaulting John Says: 'Ann
Can Sing OVA'. What Just Sing? And
Vault.":
Volts = Joules/Sec
Amps = Coulombs/Sec
Ohms = Volts/Amp
Watts = Joules/Sec=Amps x Volts


Ideal gas law [for All My Children fans] "Pine Valley
is Not Real Time"
PV=nRt


Work: formula "Lots of Work gets me Mad!":
Work = Mad:
M=Mass
a=acceleration
d=distance


Syncope (fainting) treatment If the face is red,
raise the head.
If the face is pale, raise the tail.


Hospice facets HOSPICE:
Home
Outpatient
Support groups
Pain medication/ Physical needs
Inpatient
Counseling
End-stage (terminal) illness/ Emotional needs


Healthy lifestyle modification DRAINS:
Diet
Reduce weight
Alcohol reduced
Improve circulation (exercise)
No other disease
Smoking stopped


Clinical essay plan "During Exams Please
Say Silently I Must Prepare F***ing 
W
ell":
Definition
Epidemiology
Pathology
Signs and Symptoms
Investigations
Management
Prognosis
Further Work


Safety factors SETUP:
Stop
Environment
Traffic
Unknown hazards
Protect yourself, patient, bystanders


Admission orders: general ADA VAN DISSEL:
· In order of writing on the hospital admission form:
Admit (to which ward)
Diagnosis
Allergies
Vital signs
Activities
Nursing orders (wind, wound, and water)
Diet
Intravenous
Sedation
Sleep
Elimination
Lab work


Quality of life measurement in patients FIDOH:
Functional status
Impairment
Death/ Duration of life
Opportunity
Health perception
· Functional status: Social function (limitations in usual roles, degree of
social interaction, sexual function); psychological function (affective and
cognitive); physical function.
· Impairment: Symptoms, signs, self reported disease, physiological changes.
· Death/ Duration of life: Mortality, life expectancy, disease adjusted years of
life lost
· Opportunity: How the disease has influenced the patient's ability to
participate in society as well as their psychological resilience
· Health perception: Satisfaction with health; general feeling on a day to day
basis.

Surgery Mnemonics


Surgery Mnemonics


Pancreatitis: treatment MACHINES:
Monitor vital signs
Analgesia/ Antibiotics
Calcium gluconate (if deemed necessary)
H2 receptor antagonist
IV access/ IV fluids
Nil by mouth
Empty gastric contents
Surgery if required/ Senior review


Appendicitis: Alvarado's scoring system for diagnosis 
MANTRELS
:
Migratory pain (1)
Anorexia (1)
Nausea (1)
Tenderness (2)
Rebound tenderness (1)
Elevated temperature (1)
Leucocytosis (2)
Shift to left (1)
· Score 3-4 = no appendicitis. Score 5-6 = doubtful. Score 7 or more =
appendicitis is confirmed.


Post operative order list check-up FLAVOR:
Fluids
Laboratories
Activity
Vital signs
Oral allowances
Rx [medications]


Child-Pugh classification "Pour Another Beer
AEleven":
PT
Albumin
Bilirubin
Ascites
Encephalopathy
·Scoring (each is either 1, 2 or 3 points):
PT (greater than 12 sec.): 1-3 or 4-6 or >6.
Albumin: >3.5 or 2.8-3.5 or less than 2.8
Bilirubin: less than 2 or 2-3 or >3.
Ascities: none or slight or moderate
Encephalopathy: none or 1-2 (subjective) or 3-4 (subjective)
· Interpretation:
Class A: 5-6 points (candidate for surgical liver resection).
Class B: 7-9 points (consider chemoembolization or RFA).
Class C: 10-15 points (consider options in B or no therapy).


Hernias of Abdominal Wall Think of the abdomen as a bucket,
or PAIL that contains the viscera. These are the four groups of hernias:
Pelvic hernias: obturator, perineal, sciatic
Anterior hernias: epigastric, incisional, Spigelian, supravesical,
umbilical
Inguinal hernias: indirect, direct, femoral
Lumbar hernias: inferior lumbar triangle (Petit), superior lumbar
triangle (Grynfelt)


Hernias: abdominal wall: pelvic The end products of
metabolism that are released through the pelvis, are "Pee OStool":
Perineal hernia
Obturator hernia
Sciatic hernia


Hernias: abdominal wall: lumbar triangles (with eponyms) 
PIGS
:
Petit aka Inferior lumbar triangle
Grynfelt aka Superior lumbar triangle


TPN indications "MISIPPI Burning":
Major visceral injury
IBD
Sepsis
Ileus
Post-op
Paralysis
Intestinal fistula
Burns


Surgical discharge checklist FLAG COUP:
Lucid
Ambulatory
GP letter sent
CVS checked (BP, pulse
Operation site OK
Urinating OK
Prescription


Compartment syndrome: signs and symptoms · 5 P's:
Pain
Palor
P ulseless
Paresethesia
Pressure (increased)


Oesophageal cancer risk factors PC BASTARDS:
Plummer-Vinson syndrome
Coeliac disease
Barrett's
Alcohol
Smoking
Tylosis
Achalasia
Russia (geographical distribution)
Diet
Stricture


Abdominal aortic aneurysm: genetic component AAA (3
A's) is sometimes due to a defect in the gene encoding for type III
procollagen.


Disease description: organization of answer "IA
Surgeon's Gown, Physicians May Make Some
Clinical Progress":
Incidence
Age
Sex
Geography
Predisposing factors
Macroscopic appearance
Microscopic appearance
Spread
Clinical features
Prognosis


Inguinal mass: differential "Hernias Very Much
Like TSwell":
Hernias (inguinal, femoral)
Vascular (femoral aneurysm, sapheno varyx)
Muscle (psoas abscess)
Lymph nodes
Testicle (ectopic, undescended)
Spermatic cord (lipoma, hydrocoele)


Haematocele: etiology 3T's and 2 H's:
Tumor
Torsion
Trauma
Hydrocele as a complication
Haemophilia (blood diseases)


Abdomen: inspection 5 S's:
Size
Shape
Scars
Skin lesions
Stoma


Varicose veins: symptoms AEIOU:
Aching
Eczema
Itching
Oedema
Ulceration/ Ugly (LDS, haemosiderin, varicosities)


Swollen leg: unilateral swelling causes TV BAIL:
Trauma
Venous (varicose veins, DVT, venous insufficiency)
Baker's cyst
Allergy
Inflammation (cellulitis)
Lymphoedema


Ulcers: edge types F PURE:
Flat (eg venous)
Punched-out (eg trophic, arterial)
Undetermined (eg pressure, TB)
Rolled (eg BCC)
Everted (eg SCC)


Post-operative fever causes Six W's:
Wind: pulmonary system is primary source of fever first 48 hours, may
have pneumonia
Wound: infection at surgical site
Water: check IV for phlebitis
Walk: deep venous thrombosis, due to pelvic pooling or restricted
mobility related to pain and fatigue
Whiz: urinary tract infection if urinary catheterization
Wonder drugs: drug-induced fever


Scrotum: scrotum swelling differential THE THEATRES:
Torsion
Hernia
Epididymytis, orchitis
Trauma
Hydrocoele, varicocele, hematoma
Edema
Appendix testes (torsion, hemorrhage)
Tumour
Recurrent leukemia
Epididymal cyst
Syphilis, TB


Post-operative complications (immediate) "Post-op 
PROBS
":
Pain
Primary haemorrhage
Reactionary haemorrhage
Oliguria
Basal atelectasis
Shock/ Sepsis


Fistulas: conditions preventing closure FETID:
Foreign body
Epithelialization
Tumor
Infection
Distal obstruction


Oedema causes: generalised "HILARI IS SAVE" (Hilary):
Heart failure
Iatrogenic
Liver causes
Aldosterone increased/ ADH increased
Renal cause
Inadequate protein in blood (hypoalbuminaemia)
· Causes for the inadequate protein in blood are:
Intake Inadequate (Kwashiorkor)
Secretion fro pancreas decreased (pancreatitis)
Synthesis decreased (liver failure)
Absorption decreased (Crohn's disease)
Vomit (pyloric stenosis)
Excretion increased (nephrotic)


Oedema causes: localised ALIVE:
Allergic (angio-oedema)
Lymphatic (elephantiasis)
Inflammatory (infection, injury)
VEnous (DVT, chronic venous insufficiency)


GI bleeding: causes ABCDEFGHI:
Angiodysplasia
Bowel cancer
Colitis
Diverticulitis/ Duodenal ulcer
Epitaxis/ Esophageal (cancer, esophagitis, varices)
Fistula (anal, aortaenteric)
Gastric (cancer, ulcer, gastritis)
Hemorrhoids
Infectious diarrhoea/ IBD/ Ischemic bowel


Melanoma sites "Mel SEA" (Pronounced "Mel C" from the
Spice Girls)
· Melanoma sites, in order of frequency:
Skin
Eyes
Anus


Fistulas: conditions preventing closure FRIEND:
Foreign body
Radiation
Infection/ Inflammation (Crohn)
Epithelialization
Neoplasia
Distal obstruction


Appendicectomy: complications WRAP IF HOT:
Wound infection
Respiratory (atelectasis, pneumonia)
Abscess (pelvic)
Portal pyemia
Ileus (paralytic)
Fecal fistula
Hernia (r. inguinal)
Obstruction (intestinal due to adhesions)
Thrombus (DVT)

Social & Preventive Medicine Mnemonics


Social & Preventive Medicine Mnemonics


Cigarette smoke: major carcinogens PANT:
Polynuclear aromatic hydrocarbons
Aromatic amines
Nitrosamines
Tar
· Nicotine and Carbon monoxide are Non-Carcinogenic.


Error: type I (alpha) vs. type II (beta) Type I
(Alpha) Error:
"There IAEffect" where in reality there is none.


Reliability Random Error
REduces
REliability (REproducibility)


Suicide risk factors in order of risk SOARS:
· Top 6 risk factors in order of highest to lowest risk:
Serious previous attempt
Older than 45
Alcohol
Rage history
Sex (male)


Incidence vs. prevalence Incidence: Initiate
Infection In Interval.
Prevalence: Population's Percentage Positive.


Prevention: primary vs. secondary vs. tertiary Primary:
Predisposing factors decreased.
Secondary: Severity decreased.
Tertiary: Therapy, Training.


Recall bias REcall bias is a problem with
REtrospective studies and is based on ability to
REmember.


Hill criteria for causality " 'Clowns Pursuing
Epidemiology' Commonly Behind The Silly Samples":
Consistency
Plausibility
Experimentation
Biological gradient
Coherence
Temporality
Strength of association
Specificity


Informed consent: requirements, exceptions "Sign this DOC
before we can start":
Discussion
Obtain agreement
Coercion-free
· Exceptions to informed consent are WIPE:
Waiver
Incompetent
Privilege (therapeutic privilege)
Emergency


Accuracy of test: sensitivity vs. specificity seNsitivity
of a test: related to the rate of false Negatives.
sPecificity of a test: related to the rate of false Positives.
· Alternatively written:
seNsitive: NNon-Negatives.
sPecific: Puny Psuedo-Positives.


Poisson distribution formula MNEMONIc: M to
the Nth power times E to the Minus nth Over N
factorial

Formula is: ((m^n) * (e^-n) ) / n!
· Note: the factorial (!) at the end is an inverted lowercase letter i.


Pi: value to 31 decimal places "How I want a drink,
alcoholic of course, after the heavy chapters involving quantum mechanics. One
is, yes, adequate even enough to produce some fun and pleasure for an instant,
miserably brief":
The number of letters in each subsequent word of these two sentences give the
value of pi to 3.141592653589793238462643383279
Alternatively: If only want first 6 decimal places, use the sentence "How I wish
I could calculate Pi! "


Suicide risk factors SAD PERSONS:
Sex: male
Age: young, elderly
Depression
Previous suicide attempts
Ethanol and other drugs
Reality testing/ Rational thought (loss of)
Social support lacking
Organized suicide plan
No spouse
Sickness/ Stated future intent

Rheumatology Mnemonics


Rheumatology Mnemonics


Ankylosing spondylitis: extra-articular manifestations 6
A's:
Atlanto-axial subluxation
Anterior uveitis
Apical lung fibrosis
Aortic incompetence
Amyloidosis (kidneys)
Autoimmune bowel disease (UC)


Gout: drugs and foods raising uric acid levels Drugs are 
FACT
:
Frusemide
Aspirin/ Alcohol
Cytotoxic drugs
Thiazide diuretics
Foods are SALTS:
Shellfish
Anchovies
Liver and kidney
Turkey
Sardines


Joint pain causes SOFTER TISSUE:
Sepsis
Osteoarthritis
Fractures
Tendon/muscle
Epiphyseal
Referred
Tumor
Ischaemia
Seropositive arthritides
Seronegative arthritides
Urate
Extra-articular rheumatism (such as polymylagia)


SLE (Systemic Lupus Erythematosus) diagnosis "MD SOAP 'N
HAIR
":
Malar rash
Discoid rash
Serositis
Oral ulcer
Arthritis
Photosensitivity
Neurologic abnormality
Hematologic abnormality
ANA (+)
Immunologic abnormality
Renal involvement


Asthma: treatment ASTHMA:
Adrenergics
Steroids
Theophylline
Hydration
Mask [O2 at 24%]
Antibiotics


Osteoporosis risk factors ACCESS:
Alcohol
Corticosteroid
Calcium low
Estrogen low
Smoking
Sedentary lifestyle


SLE (Systemic Lupus Erythematosus) diagnosis (ARA criteria)
DAMP AS RHINO:
Discoid rash
ANA (+)
Malar rash
Photosensitivity
Arthritis
Serositis (pleural, pericardial)
Renal involvement
Hematologic abnormality
Immunologic abnormality
Neurologic abnormality (seizures, psychosis)
Oral / nasal ulcer, Observed


Henoch schonlein purpura: signs and symptoms NAPA:
Nephritis
Arthritis, arthralgias
Purpura, palpable (especially on buttocks and lower extremities)
Abdominal pain (need to rule out intussusception)


Arthritis: juvenile idiopathic: differential ARTHRITIS:
Anxiety
Rickets and metabolic
Tumor
Hematological
Reactive arthritis
Immunological (SLE)
Trauma
Injury
Sepsis


Felty's syndrome: components SANTA:
Splenomegaly
Anaemia
Neutropenia
Thrombocytopenia
Arthritis (rheumatoid)


Carpal tunnel syndrome TINel's sign:
TINgling sensation after
Tapping on
Traumatized nerve in carpal
Tunnel syndrome


Arthritis: seronegative spondyloarthropathies PEAR:
Psoriatic arthritis
Enteropathic arthritis
Ankylosing sponylitis
Reiter's/ Reactive

Radiology Mnemonics


Radiology Mnemonics


Chest X-ray interpretation · Preliminary is ABCDEF:
AP or PA
Body position
Confirm name
Date
Exposure
Films for comparison
· Analysis is ABCDEF:
Airways (hilar adenopathy or enlargement)
Breast shadows/ Bones (rib fractures, lytic bone lesions)
Cardiac silhoutte (cardiac enlargement)/ Costophrenic angles
(pleural effusions)
Diaphragm (evidence of free air)/ Digestive tract
Edges (apices for fibrosis, pneumothorax, pleural thickening or plaques)/
Extrathoracic tissues
Fields (evidence of alveolar filling)/ Failure (alveolar air space
disease with prominent vascularity with or without pleural effusions)


Chest X-ray: cavitating lesions differential "If you see 
HOLES
 on chest X-ray, they are WEIRD":
Wegener's syndrome
Embolic (pulmonary, septic)
Infection (anaerobes, pneumocystis, TB)
Rheumatoid (necrobiotic nodules)
Developmental cysts (sequestration)
Histiocytosis
Oncological
Lymphangioleiomyomatosis
Environmental, occupational
Sarcoid
· Alternatively: L=Left atrial myxoma


T2 vs. T1 MRI scan "WW 2" (World War II):
· Water is White in a T2 scan.
· Conversely, a T1 scan shows fat as being whiter.


Elbow ossification centers, in sequence CRITOE:
Capitellum
Radial head
Internal epicondyle
Trochlea
Olecranon
External epicondyle
· In order: appear at 1357911
years; each closes 2 years later.


Chest radiograph: checklist to examine ABCDEFGHI:
Aorta
Bronchus
Cord, spinal
Diaphragm (look for hyperinflation)
Eosphagus (look for foreign body)
Fracture (ribs)
Gas (look for pneumothorax)
Heart (look for cardiomegaly)
Iatrogenic (subclavian line, pacemakers)


Osteoarthritis: x-ray signs LOSS:
Loss of joint space
Osteopyhtes
Subcondral sclerosis
Subchondral cysts


MR imaging/ spectroscopy: important metabolites "Lying
Lazy NGood Crooks Collected My insurance":
Lipid: abnormal
Lactate: abnormal
NAA
Glutamine/glutamate
Creatinine/phosphocreatinine
Choline containing compounds
Myoinositol


Chest x-ray: differential diagnoses of shadow on the upper zones of
lung fields
 5 Ts:
Thymoma
Thyroid (retrosternal)
Tuberculosis
Terrible lymphoma
Teratoma


Neck sagittal x-ray: examination checklist ABCD:
Anterior: look for swelling
Bones: examine each bone for fractures
Cartilage: look for slipped discs
Dark spots: ensure not abnormally big, or could mean excess blood


Head CT scan: evaluation checklist "Blood Can
BVery Bad":
Blood
Cistern
Brain
Ventricles
Bone


Anterior mediastinal masses 4 T's:
Teratoma
Thymoma
Testicular-type
T-cell / Hodgkin's lymphoma


Chest radiograph: checklist to examine "Pamela Found
Our Rotation Particularly Exciting; Very Highly
Commended Mainly 'Cus She Arouses":
Patient details
Film details
Objects (eg. lines, electrodes)
Rotation
Penetration
Expansion
Vessels
Hila
Costophrenic angles
Mediastinum
Cardiothoracic Ratio
Soft tissues and bones
Air (diaphragm, pneumothorax, subcut. emphysema)


Upper/apical lobe infiltration/shadowing/fibrosis: causes 
BREASTS
:
Beryllium
Radiation
Extrinsic allergic alveolitis
Ankylosing spondylitis/ Aspergillus
Sarcoidosis
TB
Siliconiosis

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